4DLJ
Human p38 MAP kinase in complex with RL163
Summary for 4DLJ
| Entry DOI | 10.2210/pdb4dlj/pdb |
| Related | 4DLI |
| Descriptor | Mitogen-activated protein kinase 14, 2-phenyl-N~4~-(2-phenylethyl)quinazoline-4,7-diamine (3 entities in total) |
| Functional Keywords | map kinase insert, transferase, lipid binding pocket, transferase-transferase inhibitor complex, transferase/transferase inhibitor |
| Biological source | Homo sapiens (human) |
| Cellular location | Cytoplasm: Q16539 |
| Total number of polymer chains | 1 |
| Total formula weight | 41949.90 |
| Authors | Gruetter, C.,Termathe, M. (deposition date: 2012-02-06, release date: 2013-01-23, Last modification date: 2023-09-13) |
| Primary citation | Getlik, M.,Simard, J.R.,Termathe, M.,Grutter, C.,Rabiller, M.,van Otterlo, W.A.,Rauh, D. Fluorophore labeled kinase detects ligands that bind within the MAPK insert of p38alpha kinase. Plos One, 7:e39713-e39713, 2012 Cited by PubMed: 22768308DOI: 10.1371/journal.pone.0039713 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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