4DG6
Crystal structure of domains 1 and 2 of LRP6
Summary for 4DG6
Entry DOI | 10.2210/pdb4dg6/pdb |
Descriptor | Low-density lipoprotein receptor-related protein 6, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, PHOSPHATE ION, ... (4 entities in total) |
Functional Keywords | 6-bladed beta propeller, sclerostin receptor, egf, wnt, mesd, signaling protein |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 71071.71 |
Authors | Ceska, T.A.,Doyle, C.,Slocombe, P. (deposition date: 2012-01-25, release date: 2012-06-13, Last modification date: 2024-11-20) |
Primary citation | Holdsworth, G.,Slocombe, P.,Doyle, C.,Sweeney, B.,Veverka, V.,Le Rich, K.,Franklin, R.J.,Brookings, D.,Turner, J.,Kennedy, J.,Garlish, R.,Shi, J.,Newnham, L.,McMillan, D.,Muzylak, M.,Carr, M.,Henry, A.J.,Ceska, T.,Robinson, M.K. Characterization of the interaction of sclerostin with the LRP family of Wnt co-receptors To be Published, |
Experimental method | X-RAY DIFFRACTION (2.9 Å) |
Structure validation
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