4D0R

Mtb InhA complex with Pyradizinone compound 1

Summary for 4D0R

• Entry DOI: 10.2210/pdb4d0r/pdb
• Related: 4D0S
• Descriptor: ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE [NADH], NICOTINAMIDE-ADENINE-DINUCLEOTIDE, 4-(4-chlorophenoxy)-6-oxo-1-phenyl-1,6-dihydropyridazine-3-carboxamide, ... (4 entities in total)
• Functional Keywords: oxidoreductase, acp enoyl reductase, methyl-thiazole
• Biological source: MYCOBACTERIUM TUBERCULOSIS
• Total number of polymer chains: 1
• Total formula weight: 29560.94

Authors

Read, J.A.,Gingell, H.,Madhavapeddi, P.,Lange, S. (deposition date: 2014-04-29, release date: 2015-05-20, Last modification date: 2024-05-08)

• Primary citation: Lange, S.; Pyridazinones: A Novel Scaffold with Excellent Physicochemical Properties and Safety Profile for a Clinically Validated Target of Mycobacterium Tuberculosis; To be Published,

Experimental method

X-RAY DIFFRACTION (2.75 Å)