4CGL
Leishmania major N-myristoyltransferase in complex with an aminoacylpyrrolidine inhibitor
Summary for 4CGL
Entry DOI | 10.2210/pdb4cgl/pdb |
Related | 4CGM 4CGN 4CGO 4CGP |
Descriptor | GLYCYLPEPTIDE N-TETRADECANOYLTRANSFERASE, MAGNESIUM ION, (3R)-3-azanyl-4-(4-chlorophenyl)-1-[(3S,4R)-3-(4-chlorophenyl)-4-(hydroxymethyl)pyrrolidin-1-yl]butan-1-one, ... (5 entities in total) |
Functional Keywords | transferase, myristoylation, inhibitor, aminoacylpyrrolidine |
Biological source | LEISHMANIA MAJOR |
Total number of polymer chains | 1 |
Total formula weight | 48919.66 |
Authors | Brannigan, J.A.,Roberts, S.M.,Bell, A.S.,Hutton, J.A.,Smith, D.F.,Tate, E.W.,Leatherbarrow, R.J.,Wilkinson, A.J. (deposition date: 2013-11-25, release date: 2014-07-09, Last modification date: 2024-05-08) |
Primary citation | Brannigan, J.A.,Roberts, S.M.,Bell, A.S.,Hutton, J.A.,Hodgkinson, M.R.,Tate, E.W.,Leatherbarrow, R.J.,Smith, D.F.,Wilkinson, A.J. Diverse Modes of Binding in Structures of Leishmania Major N-Myristoyltransferase with Selective Inhibitors Iucrj, 1:250-, 2014 Cited by PubMed: 25075346DOI: 10.1107/S2052252514013001 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.48 Å) |
Structure validation
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