4CCE
STRUCTURE OF MOUSE GALACTOCEREBROSIDASE WITH GALACTOSE: ENZYME- PRODUCT COMPLEX
Summary for 4CCE
Entry DOI | 10.2210/pdb4cce/pdb |
Related | 4CCC 4CCD |
Descriptor | GALACTOCEREBROSIDASE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-galactopyranose, ... (6 entities in total) |
Functional Keywords | hydrolase, krabbe disease, glycosyl hydrolase, lysosomal storage disease, enzyme-product complex |
Biological source | MUS MUSCULUS (HOUSE MOUSE) |
Cellular location | Lysosome (By similarity): P54818 |
Total number of polymer chains | 1 |
Total formula weight | 76311.39 |
Authors | Hill, C.H.,Graham, S.C.,Read, R.J.,Deane, J.E. (deposition date: 2013-10-21, release date: 2013-12-11, Last modification date: 2023-12-20) |
Primary citation | Hill, C.H.,Graham, S.C.,Read, R.J.,Deane, J.E. Structural Snapshots Illustrate the Catalytic Cycle of Beta-Galactocerebrosidase, the Defective Enzyme in Krabbe Disease Proc.Natl.Acad.Sci.USA, 110:20479-, 2013 Cited by PubMed: 24297913DOI: 10.1073/PNAS.1311990110 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.06 Å) |
Structure validation
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