4CAU

THREE-DIMENSIONAL STRUCTURE OF DENGUE VIRUS SEROTYPE 1 COMPLEXED WITH 2 HMAB 14C10 FAB

Summary for 4CAU

• Entry DOI: 10.2210/pdb4cau/pdb
• EMDB information: 5268
• Descriptor: ENVELOPE PROTEIN E, FAB 14C10 (2 entities in total)
• Functional Keywords: flavivirus, serotype 1, mature virus, virus, antibodies, human antibodies, monoclonal antibodies, hmab
• Biological source: DENGUE VIRUS 1; More
• Cellular location: Virion membrane ; Multi-pass membrane protein : Q689G3
• Total number of polymer chains: 5
• Total formula weight: 181466.95

Authors

Teoh, E.P.,Kukkaro, P.,Teo, E.W.,Lim, A.P.,Tan, T.T.,Yip, A.,Schul, W.,Aung, M.,Kostyuchenko, V.A.,Leo, Y.S.,Chan, S.H.,Smith, K.G.,Chan, A.H.,Zou, G.,Ooi, E.E.,Kemeny, D.M.,Tan, G.K.,Ng, J.K.,Ng, M.L.,Alonso, S.,Fisher, D.,Shi, P.Y.,Hanson, B.J.,Lok, S.M.,Macary, P.A. (deposition date: 2013-10-09, release date: 2013-10-16, Last modification date: 2017-08-23)

• Primary citation: Teoh, E.P.,Kukkaro, P.,Teo, E.W.,Lim, A.P.C.,Tan, T.T.,Yip, A.,Schul, W.,Aung, M.,Kostyuchenko, V.A.,Leo, Y.S.,Chan, S.H.,Smith, K.G.C.,Chan, A.H.Y.,Zou, G.,Ooi, E.E.,Kemeny, D.M.,Tan, G.K.,Ng, J.K.W.,Ng, M.L.,Alonso, S.,Fisher, D.,Shi, P.,Hanson, B.J.,Lok, S.,Macary, P.A.; The Structural Basis for Serotype-Specific Neutralization of Dengue Virus by a Human Antibody.; Sci.Trans.Med, 4:9RA83-, 2012; PubMed: 22723463; DOI: 10.1126/SCITRANSLMED.3003888

Experimental method

ELECTRON MICROSCOPY (7 Å)