4C4S

Structure of beta-phosphoglucomutase in complex with an alpha- fluorophosphonate analogue of beta-glucose-1-phosphate and magnesium trifluoride

Summary for 4C4S

Entry DOI	10.2210/pdb4c4s/pdb
Related	4C4R 4C4T
Descriptor	BETA-PHOSPHOGLUCOMUTASE, (1R)-1,5-anhydro-1-[(S)-fluoro(phosphono)methyl]-D-glucitol, TRIFLUOROMAGNESATE, ... (5 entities in total)
Functional Keywords	isomerase, phosphoryl transfer, transition state, metal fluoride, mutase
Biological source	LACTOCOCCUS LACTIS
Cellular location	Cytoplasm (Potential): P71447
Total number of polymer chains	1
Total formula weight	24621.35
Authors	Pellegrini, E.,Bowler, M.W. (deposition date: 2013-09-09, release date: 2014-07-16, Last modification date: 2023-12-20)
Primary citation	Jin, Y.,Bhattasali, D.,Pellegrini, E.,Forget, S.M.,Baxter, N.J.,Cliff, M.J.,Bowler, M.W.,Jakeman, D.L.,Blackburn, G.M.,Waltho, J.P. Alpha-Fluorophosphonates Reveal How a Phosphomutase Conserves Transition State Conformation Over Hexose Recognition in its Two-Step Reaction. Proc.Natl.Acad.Sci.USA, 111:12384-, 2014 Cited by PubMed: 25104750 DOI: 10.1073/PNAS.1402850111 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.5 Å)

Structure validation