4BUV
Crystal structure of human tankyrase 2 in complex with N-(4-(4-oxo-3, 4-dihydroquinazolin-2-yl)phenyl)thiophene-2-carboxamide
Summary for 4BUV
Entry DOI | 10.2210/pdb4buv/pdb |
Related | 4BU3 4BU5 4BU6 4BU7 4BU8 4BU9 4BUA 4BUD 4BUE 4BUF 4BUI 4BUS 4BUT 4BUU 4BUW 4BUX 4BUY |
Descriptor | TANKYRASE-2, ZINC ION, SULFATE ION, ... (7 entities in total) |
Functional Keywords | transferase, diphtheria toxin like fold, adp-ribosylation, transferase-transferase inhibitor complex |
Biological source | HOMO SAPIENS (HUMAN) |
Total number of polymer chains | 2 |
Total formula weight | 56113.71 |
Authors | Haikarainen, T.,Narwal, M.,Lehtio, L. (deposition date: 2013-06-24, release date: 2013-10-30, Last modification date: 2023-12-20) |
Primary citation | Haikarainen, T.,Koivunen, J.,Narwal, M.,Venkannagari, H.,Obaji, E.,Joensuu, P.,Pihlajaniemi, T.,Lehtio, L. Para-Substituted 2-Phenyl-3,4-Dihydroquinazolin-4-Ones as Potent and Selective Tankyrase Inhibitors. Chemmedchem, 8:1978-, 2013 Cited by PubMed: 24130191DOI: 10.1002/CMDC.201300337 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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