4ARW
Pseudomonas aeruginosa RmlA in complex with allosteric inhibitor
Summary for 4ARW
Entry DOI | 10.2210/pdb4arw/pdb |
Descriptor | GLUCOSE-1-PHOSPHATE THYMIDYLYLTRANSFERASE, N-(6-AMINO-1-BUTYL-2,4-DIOXO-1,2,3,4-TETRAHYDROPYRIMIDIN-5-YL)-N-METHYL-BENZENESULFONAMIDE, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ... (6 entities in total) |
Functional Keywords | transferase |
Biological source | PSEUDOMONAS AERUGINOSA |
Total number of polymer chains | 4 |
Total formula weight | 136683.74 |
Authors | Alphey, M.S.,Pirrie, L.,Torrie, L.S.,Gardiner, M.,Westwood, N.J.,Gray, D.,Naismith, J.H. (deposition date: 2012-04-26, release date: 2012-10-31, Last modification date: 2023-12-20) |
Primary citation | Alphey, M.S.,Pirrie, L.,Torrie, L.S.,Boulkeroua, W.A.,Gardiner, M.,Sarkar, A.,Maringer, M.,Oehlmann, W.,Brenk, R.,Scherman, M.S.,McNeil, M.,Rejzek, M.,Field, R.A.,Singh, M.,Gray, D.,Westwood, N.J.,Naismith, J.H. Allosteric competitive inhibitors of the glucose-1-phosphate thymidylyltransferase (RmlA) from Pseudomonas aeruginosa. ACS Chem. Biol., 8:387-396, 2013 Cited by PubMed: 23138692DOI: 10.1021/cb300426u PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.204 Å) |
Structure validation
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