4AFI

Complex between Vamp7 longin domain and fragment of delta-adaptin from AP3

Summary for 4AFI

• Entry DOI: 10.2210/pdb4afi/pdb
• Related: 2VX8
• Descriptor: AP-3 COMPLEX SUBUNIT DELTA-1, VESICLE-ASSOCIATED MEMBRANE PROTEIN 7, PRASEODYMIUM ION (3 entities in total)
• Functional Keywords: endocytosis, exocytosis, clathrin adaptor, chimera, fusion protein
• Biological source: HOMO SAPIENS (HUMAN); More
• Cellular location: Cytoplasmic vesicle, secretory vesicle membrane; Single-pass type IV membrane protein: P70280
• Total number of polymer chains: 2
• Total formula weight: 39394.30

Authors

Kent, H.M.,Evans, P.R.,Luzio, J.P.,Peden, A.A.,Owen, D.J. (deposition date: 2012-01-19, release date: 2012-05-30, Last modification date: 2023-12-20)

• Primary citation: Kent, H.M.,Evans, P.R.,Schaefer, I.B.,Gray, S.R.,Sanderson, C.M.,Luzio, J.P.,Peden, A.A.,Owen, D.J.; Structural Basis of the Intracellular Sorting of the Snare Vamp7 by the Ap3 Adaptor Complex; Dev.Cell, 22:979-, 2012; PubMed: 22521722; DOI: 10.1016/J.DEVCEL.2012.01.018

Experimental method

X-RAY DIFFRACTION (2.8 Å)