449D
5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3', BENZIMIDAZOLE DERIVATIVE COMPLEX
Summary for 449D
Entry DOI | 10.2210/pdb449d/pdb |
Descriptor | DNA (5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3'), 2'-(3-IODOPHENYL)-5-(4-METHYL-1-PIPERAZINYL)-2,5'-BI-BENZIMIDAZOLE (3 entities in total) |
Functional Keywords | b-dna, minor groove binding, dna |
Total number of polymer chains | 2 |
Total formula weight | 7862.19 |
Authors | Squire, C.J.,Baker, L.J.,Clark, G.R.,Martin, R.F.,White, J. (deposition date: 1999-01-20, release date: 2000-02-02, Last modification date: 2023-12-27) |
Primary citation | Squire, C.J.,Baker, L.J.,Clark, G.R.,Martin, R.F.,White, J. Structures of m-iodo Hoechst-DNA complexes in crystals with reduced solvent content: implications for minor groove binder drug design. Nucleic Acids Res., 28:1252-1258, 2000 Cited by PubMed: 10666470DOI: 10.1093/nar/28.5.1252 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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