3ZZN
5-Mutant (R79W, R151A, E279A, E299A,E313A) Lactate-Dehydrogenase from Thermus thermophillus
Summary for 3ZZN
| Entry DOI | 10.2210/pdb3zzn/pdb |
| Related | 2V6M 2V7P 2XXB 2XXE 2XXJ 4A73 |
| Descriptor | LACTATE DEHYDROGENASE, ADENOSINE-5'-DIPHOSPHATE (3 entities in total) |
| Functional Keywords | protein adaptation, conformational energy landscape, oxidoreductase, hyperthermophilic |
| Biological source | THERMUS THERMOPHILUS |
| Total number of polymer chains | 4 |
| Total formula weight | 131251.89 |
| Authors | Colletier, J.P.,Mraihi, S.,Madern, D. (deposition date: 2011-09-02, release date: 2012-02-08, Last modification date: 2023-12-20) |
| Primary citation | Colletier, J.P.,Aleksandrov, A.,Coquelle, N.,Mraihi, S.,Mendoza-Barbera, E.,Field, M.,Madern, D. Sampling the conformational energy landscape of a hyperthermophilic protein by engineering key substitutions. Mol. Biol. Evol., 29:1683-1694, 2012 Cited by PubMed: 22319152DOI: 10.1093/molbev/mss015 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.9 Å) |
Structure validation
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