3ZWN

Crystal structure of Aplysia cyclase complexed with substrate NGD and product cGDPR

Summary for 3ZWN

Entry DOI	10.2210/pdb3zwn/pdb
Related	1LBE 1R0S 1R12 1R15 1R16
Descriptor	ADP-RIBOSYL CYCLASE, CYCLIC GUANOSINE DIPHOSPHATE-RIBOSE, 3-(AMINOCARBONYL)-1-[(2R,3R,4S,5R)-5-({[(S)-{[(S)-{[(2R,3S,4R,5R)-5-(2-AMINO-6-OXO-1,6-DIHYDRO-9H-PURIN-9-YL)-3,4-DIHYD ROXYTETRAHYDROFURAN-2-YL]METHOXY}(HYDROXY)PHOSPHORYL]OXY}(HYDROXY)PHOSPHORYL]OXY}METHYL)-3,4-DIHYDROXYTETRAHYDROFURAN-2- YL]PYRIDINIUM, ... (4 entities in total)
Functional Keywords	hydrolase
Biological source	APLYSIA CALIFORNICA (CALIFORNIA SEA HARE)
Cellular location	Cytoplasmic vesicle: P29241
Total number of polymer chains	2
Total formula weight	60683.95
Authors	Kotaka, M.,Graeff, R.,Zhang, L.H.,Lee, H.C.,Hao, Q. (deposition date: 2011-08-02, release date: 2011-11-30, Last modification date: 2023-12-20)
Primary citation	Kotaka, M.,Graeff, R.,Chen, Z.,Zhang, L.H.,Lee, H.C.,Hao, Q. Structural Studies of Intermediates Along the Cyclization Pathway of Aplysia Adp-Ribosyl Cyclase. J.Mol.Biol., 415:514-, 2012 Cited by PubMed: 22138343 DOI: 10.1016/J.JMB.2011.11.022 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation