3ZQU

STRUCTURE OF A PROBABLE AROMATIC ACID DECARBOXYLASE

3ZQU の概要

• エントリーDOI: 10.2210/pdb3zqu/pdb
• 分子名称: PROBABLE AROMATIC ACID DECARBOXYLASE, 1-DEOXY-1-(7,8-DIMETHYL-2,4-DIOXO-3,4-DIHYDRO-2H-BENZO[G]PTERIDIN-1-ID-10(5H)-YL)-5-O-PHOSPHONATO-D-RIBITOL, SULFATE ION, ... (4 entities in total)
• 機能のキーワード: lyase
• 由来する生物種: PSEUDOMONAS AERUGINOSA
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 23035.23

構造登録者

Kopec, J.,Schnell, R.,Schneider, G. (登録日: 2011-06-11, 公開日: 2011-11-02, 最終更新日: 2023-12-20)

主引用文献

Kopec, J.,Schnell, R.,Schneider, G.
Structure of Pa4019, a Putative Aromatic Acid Decarboxylase from Pseudomonas Aeruginosa
Acta Crystallogr.,Sect.F, 67:1184-, 2011

PubMed Abstract: The ubiX gene (PA4019) of Pseudomonas aeruginosa has been annotated as encoding a putative 3-octaprenyl-4-hydroxybenzoate decarboxylase from the ubiquinone-biosynthesis pathway. Based on a transposon mutagenesis screen, this gene was also implicated as being essential for the survival of this organism. The crystal structure of recombinant UbiX determined to 1.5 Å resolution showed that the protein belongs to the superfamily of homo-oligomeric flavine-containing cysteine decarboxylases. The enzyme assembles into a dodecamer with 23 point symmetry. The subunit displays a typical Rossmann fold and contains one FMN molecule bound at the interface between two subunits.

PubMed: 22102023
DOI: 10.1107/S174430911102923X

実験手法

X-RAY DIFFRACTION (1.5 Å)