3ZMP

Src-derived peptide inhibitor complex of PTP1B

3ZMP の概要

• エントリーDOI: 10.2210/pdb3zmp/pdb
• 分子名称: TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 1, PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC (3 entities in total)
• 機能のキーワード: hydrolase-peptide complex, enzyme inhibitors, structure-activity relationship, transferase, hydrolase/peptide
• 由来する生物種: HOMO SAPIENS (HUMAN); 詳細
• 細胞内の位置: Endoplasmic reticulum membrane ; Peripheral membrane protein ; Cytoplasmic side : P18031; Cell membrane: P12931
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 79471.99

構造登録者

Temmerman, K.,Pogenberg, V.,Meyer, C.,Koehn, M.,Wilmanns, M. (登録日: 2013-02-12, 公開日: 2014-01-22, 最終更新日: 2023-12-20)

• 主引用文献: Meyer, C.,Hoeger, B.,Temmerman, K.,Tatarek-Nossol, M.,Pogenberg, V.,Bernhagen, J.,Wilmanns, M.,Kapurniotu, A.,Kohn, M.; Development of Accessible Peptidic Tool Compounds to Study the Phosphatase Ptp1B in Intact Cells.; Acs Chem.Biol., 9:769-, 2014; PubMed: 24387659; DOI: 10.1021/CB400903U

実験手法

X-RAY DIFFRACTION (2.619 Å)