3ZK5

PikC D50N mutant bound to the 10-DML analog with the 3-(N,N-dimethylamino)ethanoate anchoring group

Summary for 3ZK5

Entry DOI	10.2210/pdb3zk5/pdb
Related	4B7S
Descriptor	CYTOCHROME P450 HYDROXYLASE PIKC, PROTOPORPHYRIN IX CONTAINING FE, (3R,4S,5S,7R,9E,11R,12R)-12-ethyl-3,5,7,11-tetramethyl-2,8-dioxooxacyclododec-9-en-4-yl N,N-dimethylglycinate, ... (4 entities in total)
Functional Keywords	oxidoreductase, monooxygenase, pikromycin biosynthesis
Biological source	STREPTOMYCES VENEZUELAE
Total number of polymer chains	2
Total formula weight	98531.50
Authors	Podust, L.M. (deposition date: 2013-01-21, release date: 2014-01-29, Last modification date: 2023-12-20)
Primary citation	Negretti, S.,Narayan, A.R.H.,Chiou, K.C.,Kells, P.M.,Stachowski, J.L.,Hansen, D.A.,Podust, L.M.,Montgomery, J.,Sherman, D.H. Directing Group-Controlled Regioselectivity in an Enzymatic C-H Bond Oxygenation. J.Am.Chem.Soc., 136:4901-, 2014 Cited by PubMed: 24627965 DOI: 10.1021/JA5016052 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.89 Å)

Structure validation