3ZHS

Crystal structure of the SucA domain of Mycobacterium smegmatis KGD, first post-decarboxylation intermediate from alpha-ketoglutarate

3ZHS の概要

• エントリーDOI: 10.2210/pdb3zhs/pdb
• 関連するPDBエントリー: 3ZHQ 3ZHR 3ZHT 3ZHU 3ZHV
• 分子名称: MULTIFUNCTIONAL 2-OXOGLUTARATE METABOLISM ENZYME, (4S)-4-{3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-5-(2-{[(S)-hydroxy(phosphonooxy)phosphoryl]oxy}ethyl)-4-methyl-1,3lambda~5~-thiazol-2-yl}-4-hydroxybutanoic acid, MAGNESIUM ION, ... (5 entities in total)
• 機能のキーワード: oxidoreductase, e1o, thiamine diphosphate
• 由来する生物種: MYCOBACTERIUM SMEGMATIS
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 391033.74

構造登録者

Wagner, T.,Barilone, N.,Bellinzoni, M.,Alzari, P.M. (登録日: 2012-12-24, 公開日: 2013-11-13, 最終更新日: 2023-12-20)

• 主引用文献: Wagner, T.,Barilone, N.,Alzari, P.M.,Bellinzoni, M.; A Dual Conformation of the Post-Decarboxylation Intermediate is Associated with Distinct Enzyme States in Mycobacterial Alpha-Ketoglutarate Decarboxylase (Kgd).; Biochem.J., 457:425-, 2014; PubMed: 24171907; DOI: 10.1042/BJ20131142

実験手法

X-RAY DIFFRACTION (2.1 Å)