3ZD0

The Solution Structure of Monomeric Hepatitis C Virus p7 Yields Potent Inhibitors of Virion Release

3ZD0 の概要

• エントリーDOI: 10.2210/pdb3zd0/pdb
• NMR情報: BMRB: 18863
• 分子名称: P7 PROTEIN (1 entity in total)
• 機能のキーワード: transport protein, antiviral, ion channel, viroporin
• 由来する生物種: HEPATITIS C VIRUS (HCV)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 9065.47

構造登録者

Foster, T.L.,Sthompson, G.,Kalverda, A.P.,Kankanala, J.,Thompson, J.,Barker, A.M.,Clarke, D.,Noerenberg, M.,Pearson, A.R.,Rowlands, D.J.,Homans, S.W.,Harris, M.,Foster, R.,Griffin, S.D.C. (登録日: 2012-11-23, 公開日: 2013-09-04, 最終更新日: 2023-06-14)

• 主引用文献: Foster, T.L.,Thompson, G.S.,Kalverda, A.P.,Kankanala, J.,Bentham, M.,Wetherill, L.F.,Thompson, J.,Barker, A.M.,Clarke, D.,Noerenberg, M.,Pearson, A.R.,Rowlands, D.J.,Homans, S.W.,Harris, M.,Foster, R.,Griffin, S.D.C.; Structure-Guided Design Affirms Inhibitors of Hepatitis C Virus P7 as a Viable Class of Antivirals Targeting Virion Release; Hepatology, 59:408-, 2014; PubMed: 24022996; DOI: 10.1002/HEP.26685

実験手法

SOLUTION NMR