3ZCZ
Crystal structure of a complex between Actinomadura R39 DD-peptidase and a trifluoroketone inhibitor
Summary for 3ZCZ
Entry DOI | 10.2210/pdb3zcz/pdb |
Descriptor | D-ALANYL-D-ALANINE CARBOXYPEPTIDASE, (2R)-2-amino-7-oxo-7-{[(2R,3S)-4,4,4-trifluoro-3-hydroxybutan-2-yl]amino}heptanoic acid, SULFATE ION, ... (5 entities in total) |
Functional Keywords | hydrolase, inhibitor, peptidoglycan |
Biological source | ACTINOMADURA SP. R39 |
Cellular location | Secreted: P39045 |
Total number of polymer chains | 4 |
Total formula weight | 193843.67 |
Authors | Sauvage, E.,Herman, R.,Kerff, F.,Rocaboy, M.,Charlier, P. (deposition date: 2012-11-23, release date: 2013-03-27, Last modification date: 2023-12-20) |
Primary citation | Dzhekieva, L.,Adediran, S.A.,Herman, R.,Kerff, F.,Duez, C.,Charlier, P.,Sauvage, E.,Pratt, R.F. Inhibition of Dd-Peptidases by a Specific Trifluoroketone: Crystal Structure of a Complex with the Actinomadura R39 Dd-Peptidase. Biochemistry, 52:2128-, 2013 Cited by PubMed: 23484909DOI: 10.1021/BI400048S PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
Download full validation report