3X0W

Crystal structure of PLEKHM1 LIR-fused human LC3B_2-119

Summary for 3X0W

• Entry DOI: 10.2210/pdb3x0w/pdb
• Descriptor: Microtubule-associated proteins 1A/1B light chain 3B (2 entities in total)
• Functional Keywords: ubiquitin-like fold, autophagy, plekhm1, protein binding
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm, cytoskeleton: Q9GZQ8
• Total number of polymer chains: 2
• Total formula weight: 31463.77

Authors

Suzuki, H.,McEwan, D.G.,Popovic, D.,Gubas, A.,Terawaki, S.,Stadel, D.,Coxon, F.,Stegmann, D.M.,Bhogaraju, S.,Maddi, K.,Kirchhoff, A.,Gatti, E.,Helfrich, M.H.,Behrends, C.,Pierre, P.,Dikic, I.,Wakatsuki, S. (deposition date: 2014-10-22, release date: 2015-01-14, Last modification date: 2023-11-08)

• Primary citation: McEwan, D.G.,Popovic, D.,Gubas, A.,Terawaki, S.,Suzuki, H.,Stadel, D.,Coxon, F.P.,Miranda de Stegmann, D.,Bhogaraju, S.,Maddi, K.,Kirchof, A.,Gatti, E.,Helfrich, M.H.,Wakatsuki, S.,Behrends, C.,Pierre, P.,Dikic, I.; PLEKHM1 regulates autophagosome-lysosome fusion through HOPS complex and LC3/GABARAP proteins.; Mol.Cell, 57:39-54, 2015; PubMed: 25498145; DOI: 10.1016/j.molcel.2014.11.006

Experimental method

X-RAY DIFFRACTION (2.71 Å)