3X0B
Crystal structure of PIP4KIIBETA I368A complex with AMP
Summary for 3X0B
Entry DOI | 10.2210/pdb3x0b/pdb |
Related | 3WZZ 3X01 3X02 3X03 3X04 3X05 3X06 3X07 3X08 3X09 3X0A 3X0C |
Descriptor | Phosphatidylinositol 5-phosphate 4-kinase type-2 beta, ADENOSINE MONOPHOSPHATE (3 entities in total) |
Functional Keywords | lipid kinase, phosphoinositide signaling, transferase |
Biological source | Homo sapiens (human) |
Cellular location | Endoplasmic reticulum membrane ; Peripheral membrane protein : P78356 |
Total number of polymer chains | 2 |
Total formula weight | 91162.53 |
Authors | Takeuchi, K.,Lo, Y.H.,Sumita, K.,Senda, M.,Terakawa, J.,Dimitoris, A.,Locasale, J.W.,Sasaki, M.,Yoshino, H.,Zhang, Y.,Kahoud, E.R.,Takano, T.,Yokota, T.,Emerling, B.,Asara, J.A.,Ishida, T.,Shimada, I.,Daikoku, T.,Cantley, L.C.,Senda, T.,Sasaki, A.T. (deposition date: 2014-10-09, release date: 2015-10-14, Last modification date: 2023-11-08) |
Primary citation | Sumita, K.,Lo, Y.H.,Takeuchi, K.,Senda, M.,Kofuji, S.,Ikeda, Y.,Terakawa, J.,Sasaki, M.,Yoshino, H.,Majd, N.,Zheng, Y.,Kahoud, E.R.,Yokota, T.,Emerling, B.M.,Asara, J.M.,Ishida, T.,Locasale, J.W.,Daikoku, T.,Anastasiou, D.,Senda, T.,Sasaki, A.T. The Lipid Kinase PI5P4K beta Is an Intracellular GTP Sensor for Metabolism and Tumorigenesis Mol.Cell, 61:187-198, 2016 Cited by PubMed: 26774281DOI: 10.1016/j.molcel.2015.12.011 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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