3WU1

Crystal structure of the ETS1-RUNX1-DNA ternary complex

Summary for 3WU1

• Entry DOI: 10.2210/pdb3wu1/pdb
• Related: 3WTS 3WTT 3WTU 3WTV 3WTW 3WTX 3WTY 3WTZ 3WU0
• Descriptor: Runt-related transcription factor 1, Protein C-ets-1, DNA (5'-D(*GP*GP*AP*AP*GP*CP*CP*AP*CP*AP*TP*CP*CP*TP*CP*T)-3'), ... (5 entities in total)
• Functional Keywords: protein-dna complex, dna-binding, methylation, nucleus, phosphoprotein, transcription regulation, isopeptide bond, proto-oncogene, transcription-dna complex, transcription/dna
• Biological source: Mus musculus (mouse); More
• Cellular location: Nucleus : Q03347; Cytoplasm : P14921
• Total number of polymer chains: 4
• Total formula weight: 36308.63

Authors

Tahirov, T.H.,Ogata, K. (deposition date: 2014-04-21, release date: 2014-08-20, Last modification date: 2023-11-08)

• Primary citation: Shiina, M.,Hamada, K.,Inoue-Bungo, T.,Shimamura, M.,Uchiyama, A.,Baba, S.,Sato, K.,Yamamoto, M.,Ogata, K.; A novel allosteric mechanism on protein-DNA interactions underlying the phosphorylation-dependent regulation of Ets1 target gene expressions.; J.Mol.Biol., 427:1655-1669, 2015; PubMed: 25083921; DOI: 10.1016/j.jmb.2014.07.020

Experimental method

X-RAY DIFFRACTION (2.4 Å)