3WTH

Crystal Structure of Lymnaea stagnalis Acetylcholine-Binding Protein Q55R Mutant Complexed with Imidacloprid

3WTH の概要

• エントリーDOI: 10.2210/pdb3wth/pdb
• 関連するPDBエントリー: 2ZJU 2ZJV
• 分子名称: Acetylcholine-binding protein, (2E)-1-[(6-chloropyridin-3-yl)methyl]-N-nitroimidazolidin-2-imine (3 entities in total)
• 機能のキーワード: neonicotinoids, nicotinic acetylcholine receptor, imidacloprid, acetylcholine binding, signaling protein
• 由来する生物種: Lymnaea stagnalis (Great pond snail)
• 細胞内の位置: Secreted: P58154
• タンパク質・核酸の鎖数: 5
• 化学式量合計: 122532.68

構造登録者

Okajima, T.,Ihara, M.,Yamashita, A.,Oda, T.,Matsuda, K. (登録日: 2014-04-11, 公開日: 2015-02-04)

• 主引用文献: Ihara, M.,Okajima, T.,Yamashita, A.,Oda, T.,Asano, T.,Matsui, M.,Sattelle, D.B.,Matsuda, K.; Studies on an acetylcholine binding protein identify a basic residue in loop G on the beta 1 strand as a new structural determinant of neonicotinoid actions; Mol.Pharmacol., 86:736-746, 2014; PubMed: 25267717; DOI: 10.1124/mol.114.094698

実験手法

X-RAY DIFFRACTION (2.54 Å)