3WSR

Crystal structure of CLEC-2 in complex with O-glycosylated podoplanin

3WSR の概要

• エントリーDOI: 10.2210/pdb3wsr/pdb
• 関連するPDBエントリー: 2C6U
• 分子名称: C-type lectin domain family 1 member B, Peptide from Podoplanin, beta-D-galactopyranose-(1-3)-[N-acetyl-alpha-neuraminic acid-(2-6)]2-acetamido-2-deoxy-alpha-D-galactopyranose, ... (4 entities in total)
• 機能のキーワード: c-type lectin fold, cell surface receptor, podoplanin, o-glycosylated, extracellular region, sugar binding protein
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 35071.00

構造登録者

Nagae, M.,Morita-Matsumoto, K.,Kato, M.,Kato-Kaneko, M.,Kato, Y.,Yamaguchi, Y. (登録日: 2014-03-20, 公開日: 2014-10-22, 最終更新日: 2023-11-08)

• 主引用文献: Nagae, M.,Morita-Matsumoto, K.,Kato, M.,Kato-Kaneko, M.,Kato, Y.,Yamaguchi, Y.; A Platform of C-type Lectin-like Receptor CLEC-2 for Binding O-Glycosylated Podoplanin and Nonglycosylated Rhodocytin; Structure, 22:1711-1721, 2014; PubMed: 25458834; DOI: 10.1016/j.str.2014.09.009

実験手法

X-RAY DIFFRACTION (1.91 Å)