3WS3

Crystal Structure of H-2D in complex with an insulin derived peptide

3WS3 の概要

• エントリーDOI: 10.2210/pdb3ws3/pdb
• 関連するPDBエントリー: 3WS6
• 分子名称: H-2 class I histocompatibility antigen, D-B alpha chain, Beta-2-microglobulin, Insulin derived 9-mer peptide, ... (4 entities in total)
• 機能のキーワード: class i mhc, major histocompatibility complex, insulin, h-2d, structural genomics, psi-biology, new york structural genomics research consortium, nysgrc, immune system
• 由来する生物種: Mus musculus (mouse); 詳細
• 細胞内の位置: Membrane; Single-pass type I membrane protein: P01899; Secreted: P01887
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 89484.39

構造登録者

Kumar, P.R.,Mukherjee, G.,Samanta, D.,DiLorenzo, T.P.,Almo, S.C.,Immune Function Network,New York Structural Genomics Research Consortium (NYSGRC) (登録日: 2014-02-28, 公開日: 2014-03-26, 最終更新日: 2023-11-08)

• 主引用文献: Lamont, D.,Mukherjee, G.,Kumar, P.R.,Samanta, D.,McPhee, C.G.,Kay, T.W.H.,Almo, S.C.,DiLorenzo, T.P.,Serreze, D.V.; Compensatory mechanisms allow undersized anchor-deficient class I MHC ligands to mediate pathogenic autoreactive T cell responses; J. Immunol., 193:2135-2146, 2014; PubMed: 25063871; DOI: 10.4049/jimmunol.1400997

実験手法

X-RAY DIFFRACTION (2.335 Å)