3W7R

Structure of Human dihydroorotate dehydrogenase in complex with mii-4-097

Summary for 3W7R

• Entry DOI: 10.2210/pdb3w7r/pdb
• Related: 3W71
• Descriptor: Dihydroorotate dehydrogenase (quinone), mitochondrial, CHLORIDE ION, DECYLAMINE-N,N-DIMETHYL-N-OXIDE, ... (10 entities in total)
• Functional Keywords: rossmann fold, oxidoreductase, dihydroorotate/orotate and ubiquinone/ubiquinol, mitochondrial inner membrane, oxidoreductase-oxidoreductase inhibitor complex, oxidoreductase/oxidoreductase inhibitor
• Biological source: Homo sapiens (human)
• Cellular location: Mitochondrion inner membrane; Single-pass membrane protein: Q02127
• Total number of polymer chains: 1
• Total formula weight: 47652.37

Authors

Inaoka, D.K.,Iida, M.,Tabuchi, T.,Lee, N.,Hashimoto, S.,Matsuoka, S.,Kuranaga, T.,Shiba, T.,Sakamoto, K.,Suzuki, S.,Balogun, E.O.,Nara, T.,Aoki, T.,Inoue, M.,Honma, T.,Tanaka, A.,Harada, S.,Kita, K. (deposition date: 2013-03-06, release date: 2014-03-12, Last modification date: 2023-11-08)

• Primary citation: Inaoka, D.K.,Iida, M.,Tabuchi, T.,Lee, N.,Hashimoto, S.,Matsuoka, S.,Kuranaga, T.,Shiba, T.,Sakamoto, K.,Suzuki, S.,Balogun, E.O.,Nara, T.,Aoki, T.,Inoue, M.,Honma, T.,Tanaka, A.,Harada, S.,Kita, K.; Structure of Human dihydroorotate dehydrogenase in complex with mii-4-097; To be Published,

Experimental method

X-RAY DIFFRACTION (1.68 Å)