3W6V

Crystal structure of the DNA-binding domain of AdpA, the global transcriptional factor, in complex with a target DNA

3W6V の概要

• エントリーDOI: 10.2210/pdb3w6v/pdb
• 分子名称: AdpA, DNA (5'-D(*CP*TP*GP*TP*GP*AP*AP*CP*CP*CP*GP*CP*CP*AP*AP*C)-3'), DNA (5'-D(*AP*GP*GP*TP*TP*GP*GP*CP*GP*GP*GP*TP*TP*CP*AP*C)-3'), ... (4 entities in total)
• 機能のキーワード: h-t-h motif, sequence-specific dna binding transcription factor activity, dna-binding, intracellular, transcription activator-dna complex, transcription activator/dna
• 由来する生物種: Streptomyces griseus
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 26542.15

構造登録者

Yao, M.D.,Ohtsuka, J.,Nagata, K.,Miyazono, K.,Ohnishi, Y.,Tanokura, M. (登録日: 2013-02-22, 公開日: 2013-09-18, 最終更新日: 2023-11-08)

• 主引用文献: Yao, M.D.,Ohtsuka, J.,Nagata, K.,Miyazono, K.,Zhi, Y.,Ohnishi, Y.,Tanokura, M.; Complex Structure of the DNA-binding Domain of AdpA, the Global Transcription Factor in Streptomyces griseus, and a Target Duplex DNA Reveals the Structural Basis of Its Tolerant DNA Sequence Specificity; J.Biol.Chem., 288:31019-31029, 2013; PubMed: 24019524; DOI: 10.1074/jbc.M113.473611

実験手法

X-RAY DIFFRACTION (2.95 Å)