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3W55

The structure of ERK2 in complex with FR148083

Replaces:  2E14
Summary for 3W55
Entry DOI10.2210/pdb3w55/pdb
DescriptorMitogen-activated protein kinase 1, (3S,5Z,8S,9S,11E)-8,9,16-trihydroxy-14-methoxy-3-methyl-3,4,9,10-tetrahydro-1H-2-benzoxacyclotetradecine-1,7(8H)-dione (3 entities in total)
Functional Keywordsprotein kinase, transferase, transferase-transferase inhibitor complex, transferase/transferase inhibitor
Biological sourceHomo sapiens (human)
Cellular locationNucleus: P28482
Total number of polymer chains1
Total formula weight42593.81
Authors
Ohori, M.,Kinoshita, T. (deposition date: 2013-01-21, release date: 2013-02-06, Last modification date: 2023-11-08)
Primary citationOhori, M.,Kinoshita, T.,Yoshimura, S.,Warizaya, M.,Nakajima, H.,Miyake, H.
Role of a cysteine residue in the active site of ERK and the MAPKK family
Biochem.Biophys.Res.Commun., 353:633-637, 2007
Cited by
PubMed: 17194451
DOI: 10.1016/j.bbrc.2006.12.083
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (3 Å)
Structure validation

217705

건을2024-03-27부터공개중

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