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3W1S

Crystal structure of Saccharomyces cerevisiae Atg12-Atg5 conjugate bound to the N-terminal domain of Atg16

Summary for 3W1S
Entry DOI10.2210/pdb3w1s/pdb
DescriptorAutophagy protein 5, Autophagy protein 16, Ubiquitin-like protein ATG12, ... (4 entities in total)
Functional Keywordsubiquitin fold, e3-like, atg3 binding, isopeptide bond between atg12 gly186 and atg5 lys149, ligase
Biological sourceSaccharomyces cerevisiae S288c (Baker's yeast)
More
Cellular locationCytoplasm: Q12380
Preautophagosomal structure membrane; Peripheral membrane protein: Q03818 P38316
Total number of polymer chains3
Total formula weight48754.49
Authors
Noda, N.N.,Fujioka, Y.,Hanada, T.,Ohsumi, Y.,Inagaki, F. (deposition date: 2012-11-20, release date: 2012-12-26, Last modification date: 2023-11-08)
Primary citationNoda, N.N.,Fujioka, Y.,Hanada, T.,Ohsumi, Y.,Inagaki, F.
Structure of the Atg12-Atg5 conjugate reveals a platform for stimulating Atg8-PE conjugation
Embo Rep., 14:206-211, 2013
Cited by
PubMed: 23238393
DOI: 10.1038/embor.2012.208
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.6 Å)
Structure validation

217705

건을2024-03-27부터공개중

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