3VYP

Crystal structure of Mycobacterium tuberculosis L,D-transpeptidase LdtMt2-N140 adduct with meropenem

Summary for 3VYP

Entry DOI	10.2210/pdb3vyp/pdb
Related	3VYN 3VYO
Descriptor	Probable conserved lipoprotein LPPS, GLYCEROL, (2S,3R,4S)-4-{[(3S,5R)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl}-2-[(2S,3R)-3-hydroxy-1-oxobutan-2-yl]-3-methyl-3,4-dihydro-2H-pyrrole-5-carboxylic acid, ... (4 entities in total)
Functional Keywords	beta barrel, ykud domain, l, d-transpeptidase, beta-lactam binding, transferase
Biological source	Mycobacterium tuberculosis
Total number of polymer chains	2
Total formula weight	59516.02
Authors	Li, W.J.,Li, D.F.,Bi, L.J.,Wang, D.C. (deposition date: 2012-09-30, release date: 2013-06-19, Last modification date: 2023-11-08)
Primary citation	Li, W.J.,Li, D.F.,Hu, Y.L.,Zhang, X.E.,Bi, L.J.,Wang, D.C. Crystal structure of L,D-transpeptidase LdtMt2 in complex with meropenem reveals the mechanism of carbapenem against Mycobacterium tuberculosis Cell Res., 23:728-731, 2013 Cited by PubMed: 23588382 DOI: 10.1038/cr.2013.53 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.4 Å)

Structure validation