3VYB
Crystal structure of methyl CpG binding domain of MBD4 in complex with the 5mCG/hmCG sequence
Summary for 3VYB
Entry DOI | 10.2210/pdb3vyb/pdb |
Related | 3VXV 3VXX 3VYQ |
Descriptor | Methyl-CpG-binding domain protein 4, DNA (5'-D(*GP*TP*CP*AP*CP*TP*AP*CP*(5CM)P*GP*GP*AP*CP*A)-3'), DNA (5'-D(*GP*TP*CP*(5HC)P*GP*GP*TP*AP*GP*TP*GP*AP*CP*T)-3'), ... (6 entities in total) |
Functional Keywords | methyl cpg binding domain, protein-dna complex, versatile base recognition, hydrolase-dna complex, hydrolase/dna |
Biological source | Mus musculus (mouse) |
Cellular location | Nucleus: Q9Z2D7 |
Total number of polymer chains | 3 |
Total formula weight | 16555.84 |
Authors | Otani, J.,Arita, K.,Kato, T.,Kinoshita, M.,Ariyoshi, M.,Shirakawa, M. (deposition date: 2012-09-22, release date: 2013-01-16, Last modification date: 2024-10-09) |
Primary citation | Otani, J.,Arita, K.,Kato, T.,Kinoshita, M.,Kimura, H.,Suetake, I.,Tajima, S.,Ariyoshi, M.,Shirakawa, M. Structural basis of the versatile DNA recognition ability of the methyl-CpG binding domain of methyl-CpG binding domain protein 4 J.Biol.Chem., 288:6351-6362, 2013 Cited by PubMed: 23316048DOI: 10.1074/jbc.M112.431098 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
Download full validation report