3VTK

THYMIDINE KINASE FROM HERPES SIMPLEX VIRUS TYPE 1 IN COMPLEX WITH ADP AND 5-IODO-DEOXYURIDINE-MONOPHOSPHATE

3VTK の概要

• エントリーDOI: 10.2210/pdb3vtk/pdb
• 分子名称: THYMIDINE KINASE, ADENOSINE-5'-DIPHOSPHATE, 5-IODO-2'-DEOXYURIDINE-5'-MONOPHOSPHATE, ... (4 entities in total)
• 機能のキーワード: key enzyme in thymidine salvage pathway, additional thymidylate kinase activity, target for anti-herpes viral drugs, transferase
• 由来する生物種: Herpes simplex virus (type 1 / strain F)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 38066.88

構造登録者

Wild, K.,Schulz, G.E. (登録日: 1997-04-01, 公開日: 1997-10-22, 最終更新日: 2024-02-28)

• 主引用文献: Wild, K.,Bohner, T.,Folkers, G.,Schulz, G.E.; The structures of thymidine kinase from herpes simplex virus type 1 in complex with substrates and a substrate analogue.; Protein Sci., 6:2097-2106, 1997; PubMed: 9336833

実験手法

X-RAY DIFFRACTION (3 Å)