3VFQ
Human PARP14 (ARTD8, BAL2) - macro domains 1 and 2 in complex with adenosine-5-diphosphoribose
Summary for 3VFQ
Entry DOI | 10.2210/pdb3vfq/pdb |
Related | 4D86 |
Descriptor | Poly [ADP-ribose] polymerase 14, [(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL [HYDROXY-[[(2R,3S,4R,5S)-3,4,5-TRIHYDROXYOXOLAN-2-YL]METHOXY]PHOSPHORYL] HYDROGEN PHOSPHATE (2 entities in total) |
Functional Keywords | transferase, adp-ribose, parp14, macro, bal2, artd8, structural genomics, structural genomics consortium, sgc |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus: Q460N5 |
Total number of polymer chains | 1 |
Total formula weight | 45266.73 |
Authors | Karlberg, T.,Thorsell, A.G.,Arrowsmith, C.H.,Bountra, C.,Edwards, A.M.,Ekblad, T.,Weigelt, J.,Schuler, H.,Structural Genomics Consortium (SGC) (deposition date: 2012-01-10, release date: 2013-03-13, Last modification date: 2023-09-13) |
Primary citation | Forst, A.H.,Karlberg, T.,Herzog, N.,Thorsell, A.G.,Gross, A.,Feijs, K.L.,Verheugd, P.,Kursula, P.,Nijmeijer, B.,Kremmer, E.,Kleine, H.,Ladurner, A.G.,Schuler, H.,Luscher, B. Recognition of Mono-ADP-Ribosylated ARTD10 Substrates by ARTD8 Macrodomains. Structure, 21:462-475, 2013 Cited by PubMed: 23473667DOI: 10.1016/j.str.2012.12.019 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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