3VEX

Crystal structure of the O-carbamoyltransferase TobZ H14N variant in complex with carbamoyl adenylate intermediate

3VEX の概要

• エントリーDOI: 10.2210/pdb3vex/pdb
• 関連するPDBエントリー: 3VEN 3VEO 3VER 3VES 3VET 3VEW 3VEZ 3VF2 3VF4
• 分子名称: O-carbamoyltransferase TobZ, FE (II) ION, 5'-O-[(S)-(carbamoyloxy)(hydroxy)phosphoryl]adenosine, ... (6 entities in total)
• 機能のキーワード: antibiotic biosynthesis, substrate assisted catalysis, substrate channeling, adenylation, structural enzymology, enzyme evolution, transferase
• 由来する生物種: Streptoalloteichus tenebrarius (Streptomyces tenebrarius)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 64251.54

構造登録者

Parthier, C.,Stubbs, M.T.,Goerlich, S.,Jaenecke, F. (登録日: 2012-01-09, 公開日: 2012-01-25, 最終更新日: 2023-09-13)

• 主引用文献: Parthier, C.,Gorlich, S.,Jaenecke, F.,Breithaupt, C.,Brauer, U.,Fandrich, U.,Clausnitzer, D.,Wehmeier, U.F.,Bottcher, C.,Scheel, D.,Stubbs, M.T.; The O-Carbamoyltransferase TobZ Catalyzes an Ancient Enzymatic Reaction.; Angew.Chem.Int.Ed.Engl., 51:4046-4052, 2012; PubMed: 22383337; DOI: 10.1002/anie.201108896

実験手法

X-RAY DIFFRACTION (1.9 Å)