3VEV

Glucokinase in complex with an activator and glucose

3VEV の概要

• エントリーDOI: 10.2210/pdb3vev/pdb
• 関連するPDBエントリー: 3S41 3VEY 3VF6
• 分子名称: Glucokinase, alpha-D-glucopyranose, (2S)-3-cyclopentyl-N-(5-methylpyridin-2-yl)-2-[2-oxo-4-(trifluoromethyl)pyridin-1(2H)-yl]propanamide, ... (5 entities in total)
• 機能のキーワード: catalysis reaction, transferase, transferase-transferase activator complex, transferase/transferase activator
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 53592.74

構造登録者

Liu, S. (登録日: 2012-01-09, 公開日: 2012-02-08, 最終更新日: 2023-09-13)

• 主引用文献: Liu, S.,Ammirati, M.J.,Song, X.,Knafels, J.D.,Zhang, J.,Greasley, S.E.,Pfefferkorn, J.A.,Qiu, X.; Insights into Mechanism of Glucokinase Activation: OBSERVATION OF MULTIPLE DISTINCT PROTEIN CONFORMATIONS.; J.Biol.Chem., 287:13598-13610, 2012; PubMed: 22298776; DOI: 10.1074/jbc.M111.274126

実験手法

X-RAY DIFFRACTION (1.8 Å)