3VD5
E. coli (lacZ) beta-galactosidase (N460S)
Summary for 3VD5
Entry DOI | 10.2210/pdb3vd5/pdb |
Related | 1DP0 3VD3 3VD4 3VD7 3VD9 3VDA 3VDB 3VDC |
Descriptor | Beta-galactosidase, MAGNESIUM ION, SODIUM ION, ... (5 entities in total) |
Functional Keywords | transition state stabilization, substrate binding, 2-stage binding, tim barrel (alpha/beta barrel), jelly-roll barrel, immunoglobulin, beta supersandwich, glycosidase, hydrolase |
Biological source | Escherichia coli |
Total number of polymer chains | 4 |
Total formula weight | 481189.43 |
Authors | Wheatley, R.W.,Kappelhoff, J.C.,Hahn, J.N.,Dugdale, M.L.,Dutkoski, M.J.,Tamman, S.D.,Fraser, M.E.,Huber, R.E. (deposition date: 2012-01-04, release date: 2012-04-11, Last modification date: 2023-09-13) |
Primary citation | Wheatley, R.W.,Kappelhoff, J.C.,Hahn, J.N.,Dugdale, M.L.,Dutkoski, M.J.,Tamman, S.D.,Fraser, M.E.,Huber, R.E. Substitution for Asn460 cripples {beta}-galactosidase (Escherichia coli) by increasing substrate affinity and decreasing transition state stability. Arch.Biochem.Biophys., 521:51-61, 2012 Cited by PubMed: 22446164DOI: 10.1016/j.abb.2012.03.014 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
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