3V8X

The crystal structure of transferrin binding protein A (TbpA) from Neisserial meningitidis serogroup B in complex with full length human transferrin

3V8X の概要

• エントリーDOI: 10.2210/pdb3v8x/pdb
• 関連するPDBエントリー: 3V83 3V89 3V8U
• 分子名称: Transferrin-binding protein 1, Serotransferrin, N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-alpha-D-mannopyranose-(1-3)-[beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total)
• 機能のキーワード: iron binding protein, transferrin binding protein a, iron binding/scavenging, membrane protein-metal transport complex, membrane protein/metal transport
• 由来する生物種: Neisseria meningitidis serogroup B; 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 182683.46

構造登録者

Noinaj, N.,Easley, N.,Buchanan, S.K. (登録日: 2011-12-23, 公開日: 2012-02-29, 最終更新日: 2020-07-29)

• 主引用文献: Noinaj, N.,Easley, N.C.,Oke, M.,Mizuno, N.,Gumbart, J.,Boura, E.,Steere, A.N.,Zak, O.,Aisen, P.,Tajkhorshid, E.,Evans, R.W.,Gorringe, A.R.,Mason, A.B.,Steven, A.C.,Buchanan, S.K.; Structural basis for iron piracy by pathogenic Neisseria.; Nature, 483:53-58, 2012; PubMed: 22327295; DOI: 10.1038/nature10823

実験手法

X-RAY DIFFRACTION (2.6 Å)