3V6E
Crystal Structure of USP2 and a mutant form of Ubiquitin
Summary for 3V6E
Entry DOI | 10.2210/pdb3v6e/pdb |
Descriptor | Ubiquitin carboxyl-terminal hydrolase 2, Ubiquitin, ZINC ION, ... (6 entities in total) |
Functional Keywords | structural genomics, structural genomics consortium, sgc, ubiquitin, protease, hydrolase-signaling protein complex, hydrolase/signaling protein |
Biological source | Homo sapiens (human) More |
Cellular location | Cytoplasm . Isoform 4: Nucleus : O75604 Ubiquitin: Cytoplasm : P0CG48 |
Total number of polymer chains | 2 |
Total formula weight | 52743.88 |
Authors | Neculai, M.,Ernst, A.,Sidhu, S.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Weigelt, J.,Dhe-Paganon, S.,Structural Genomics Consortium (SGC) (deposition date: 2011-12-19, release date: 2012-12-19, Last modification date: 2023-09-13) |
Primary citation | Ernst, A.,Avvakumov, G.,Tong, J.,Fan, Y.,Zhao, Y.,Alberts, P.,Persaud, A.,Walker, J.R.,Neculai, A.M.,Neculai, D.,Vorobyov, A.,Garg, P.,Beatty, L.,Chan, P.K.,Juang, Y.C.,Landry, M.C.,Yeh, C.,Zeqiraj, E.,Karamboulas, K.,Allali-Hassani, A.,Vedadi, M.,Tyers, M.,Moffat, J.,Sicheri, F.,Pelletier, L.,Durocher, D.,Raught, B.,Rotin, D.,Yang, J.,Moran, M.F.,Dhe-Paganon, S.,Sidhu, S.S. A strategy for modulation of enzymes in the ubiquitin system. Science, 339:590-595, 2013 Cited by PubMed: 23287719DOI: 10.1126/science.1230161 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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