3V4O
Human MALT1 (caspase domain) in complex with an irreversible peptidic inhibitor
Summary for 3V4O
Entry DOI | 10.2210/pdb3v4o/pdb |
Related | 3V4L 3V55 |
Related PRD ID | PRD_001076 |
Descriptor | Mucosa-associated lymphoid tissue lymphoma translocation protein 1, MALT1 Inhibitor (3 entities in total) |
Functional Keywords | caspase, hydrolase, traf6, bcl10, cytosolic, hydrolase-inhibitor complex, hydrolase/inhibitor |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm, perinuclear region : Q9UDY8 |
Total number of polymer chains | 2 |
Total formula weight | 28407.04 |
Authors | Renatus, M.,Wiesmann, C. (deposition date: 2011-12-15, release date: 2012-03-14, Last modification date: 2023-11-29) |
Primary citation | Wiesmann, C.,Leder, L.,Blank, J.,Bernardi, A.,Melkko, S.,Decock, A.,D'Arcy, A.,Villard, F.,Erbel, P.,Hughes, N.,Freuler, F.,Nikolay, R.,Alves, J.,Bornancin, F.,Renatus, M. Structural Determinants of MALT1 Protease Activity. J.Mol.Biol., 419:4-21, 2012 Cited by PubMed: 22366302DOI: 10.1016/j.jmb.2012.02.018 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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