3V45

Crystal Structure of de novo designed serine hydrolase OSH55, Northeast Structural Genomics Consortium Target OR130

3V45 の概要

• エントリーDOI: 10.2210/pdb3v45/pdb
• 関連するPDBエントリー: 2DX6
• 分子名称: Serine hydrolase OSH55, CHLORIDE ION, SODIUM ION, ... (4 entities in total)
• 機能のキーワード: structural genomics, psi-biology, protein structure initiative, northeast structural genomics consortium, nesg, de novo design, de novo protein
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 17756.68

構造登録者

Kuzin, A.,Su, M.,Seetharaman, J.,Maglaqui, M.,Xiao, R.,Kohan, E.,Rajagopalan, S.,Everett, J.K.,Nair, R.,Acton, T.B.,Rost, B.,Baker, D.,Montelione, G.T.,Tong, L.,Hunt, J.F.,Northeast Structural Genomics Consortium (NESG) (登録日: 2011-12-14, 公開日: 2012-01-04, 最終更新日: 2023-09-13)

• 主引用文献: Rajagopalan, S.,Wang, C.,Yu, K.,Kuzin, A.P.,Richter, F.,Lew, S.,Miklos, A.E.,Matthews, M.L.,Seetharaman, J.,Su, M.,Hunt, J.F.,Cravatt, B.F.,Baker, D.; Design of activated serine-containing catalytic triads with atomic-level accuracy.; Nat.Chem.Biol., 10:386-391, 2014; PubMed: 24705591; DOI: 10.1038/nchembio.1498

実験手法

X-RAY DIFFRACTION (2.6 Å)