3V3V

Structural and functional analysis of quercetagetin, a natural JNK1 inhibitor

Summary for 3V3V

• Entry DOI: 10.2210/pdb3v3v/pdb
• Related: 1UKH
• Descriptor: Mitogen-activated protein kinase 8, C-Jun-amino-terminal kinase-interacting protein 1, 3,5,6,7-TETRAHYDROXY-2-(3,4-DIHYDROXYPHENYL)-4H-CHROMEN-4-ONE, ... (6 entities in total)
• Functional Keywords: transferase, phosphorylation, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• Biological source: Homo sapiens (human); More
• Cellular location: Cytoplasm: P45983; Cytoplasm (By similarity): Q9WVI9
• Total number of polymer chains: 2
• Total formula weight: 46038.17

Authors

Baek, S.,Kang, N.J.,Popowicz, G.M.,Arciniega, M.,Jung, S.K.,Byun, S.,Song, N.R.,Heo, Y.S.,Kim, B.Y.,Lee, H.J.,Holak, T.A.,Augustin, M.,Bode, A.M.,Huber, R.,Dong, Z.,Lee, K.W. (deposition date: 2011-12-14, release date: 2012-12-05, Last modification date: 2023-09-13)

• Primary citation: Baek, S.,Kang, N.J.,Popowicz, G.M.,Arciniega, M.,Jung, S.K.,Byun, S.,Song, N.R.,Heo, Y.S.,Kim, B.Y.,Lee, H.J.,Holak, T.A.,Augustin, M.,Bode, A.M.,Huber, R.,Dong, Z.,Lee, K.W.; Structural and Functional Analysis of the Natural JNK1 Inhibitor Quercetagetin.; J.Mol.Biol., 425:411-423, 2013; PubMed: 23142567; DOI: 10.1016/j.jmb.2012.10.019

Experimental method

X-RAY DIFFRACTION (2.7 Å)