3V3Q
Crystal Structure of Human Nur77 Ligand-binding Domain in Complex with Ethyl 2-[2,3,4 trimethoxy-6(1-octanoyl)phenyl]acetate
Summary for 3V3Q
Entry DOI | 10.2210/pdb3v3q/pdb |
Related | 3V3E |
Descriptor | Nuclear receptor subfamily 4 group A member 1, ethyl (2,3,4-trimethoxy-6-octanoylphenyl)acetate, GLYCEROL, ... (5 entities in total) |
Functional Keywords | orphan nuclear receptor, protein-antagonist complex, transcription, transcription-antagonist complex, transcription/antagonist |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus: P22736 |
Total number of polymer chains | 2 |
Total formula weight | 58642.93 |
Authors | |
Primary citation | Zhan, Y.,Chen, Y.,Zhang, Q.,Zhuang, J.,Tian, M.,Chen, H.,Zhang, L.,Zhang, H.,He, J.,Wang, W.,Wu, R.,Wang, Y.,Shi, C.,Yang, K.,Li, A.,Xin, Y.,Li, T.Y.,Yang, J.Y.,Zheng, Z.,Yu, C.,Lin, S.,Chang, C.,Huang, P.,Lin, T.,Wu, Q. The orphan nuclear receptor Nur77 regulates LKB1 localization and activates AMPK Nat.Chem.Biol., 8:897-904, 2012 Cited by PubMed: 22983157DOI: 10.1038/nchembio.1069 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.22 Å) |
Structure validation
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