3V31

Crystal Structure of the Peptide Bound Complex of the Ankyrin Repeat Domains of Human ANKRA2

Summary for 3V31

• Entry DOI: 10.2210/pdb3v31/pdb
• Related: 3SO8 3V2O 3V2X
• Descriptor: Ankyrin repeat family A protein 2, Histone deacetylase 4, CHLORIDE ION, ... (5 entities in total)
• Functional Keywords: structural genomics consortium, sgc, ankra2, ank repeat, protein binding, hdac4
• Biological source: Homo sapiens (human); More
• Cellular location: Cytoplasm, cytoskeleton : Q9H9E1; Nucleus: P56524
• Total number of polymer chains: 2
• Total formula weight: 20075.14

Authors

Lam, R.,Xu, C.,Bian, C.B.,Kania, J.,Bountra, C.,Weigelt, J.,Arrowsmith, C.H.,Edwards, A.M.,Bochkarev, A.,Min, J.,Structural Genomics Consortium (SGC) (deposition date: 2011-12-12, release date: 2012-04-04, Last modification date: 2023-09-13)

• Primary citation: Xu, C.,Jin, J.,Bian, C.,Lam, R.,Tian, R.,Weist, R.,You, L.,Nie, J.,Bochkarev, A.,Tempel, W.,Tan, C.S.,Wasney, G.A.,Vedadi, M.,Gish, G.D.,Arrowsmith, C.H.,Pawson, T.,Yang, X.J.,Min, J.; Sequence-Specific Recognition of a PxLPxI/L Motif by an Ankyrin Repeat Tumbler Lock.; Sci.Signal., 5:ra39-ra39, 2012; PubMed: 22649097; DOI: 10.1126/scisignal.2002979

Experimental method

X-RAY DIFFRACTION (1.57 Å)