3V2B

Human poly(adp-ribose) polymerase 15 (ARTD7, BAL3), macro domain 2 in complex with adenosine-5-diphosphoribose

「3KH6」から置き換えられました

3V2B の概要

• エントリーDOI: 10.2210/pdb3v2b/pdb
• 分子名称: Poly [ADP-ribose] polymerase 15, [(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL [HYDROXY-[[(2R,3S,4R,5S)-3,4,5-TRIHYDROXYOXOLAN-2-YL]METHOXY]PHOSPHORYL] HYDROGEN PHOSPHATE (3 entities in total)
• 機能のキーワード: structural genomics, structural genomics consortium, sgc, poly (adp-ribose) polymerase, adp-ribose, bal3, b-aggressive lymphoma protein 3, glycosyltransferase, nucleus, transcription, transcription regulation, transferase, adp-ribosylation
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Nucleus (Probable): Q460N3
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 22149.92

構造登録者

Karlberg, T.,Moche, M.,Arrowsmith, C.H.,Berglund, H.,Bountra, C.,Collins, R.,Edwards, A.M.,Flodin, S.,Flores, A.,Graslund, S.,Hammarstrom, M.,Johansson, I.,Kallas, A.,Kotenyova, T.,Kotzcsh, A.,Kraulis, P.,Nielsen, T.K.,Nordlund, P.,Nyman, T.,Persson, C.,Roos, A.K.,Schutz, P.,Siponen, M.I.,Thorsell, A.G.,Tresaugues, L.,Van den berg, S.,Weigelt, J.,Welin, M.,Wisniewska, M.,Schuler, H.,Structural Genomics Consortium (SGC) (登録日: 2011-12-12, 公開日: 2011-12-21, 最終更新日: 2024-05-29)

• 主引用文献: Forst, A.H.,Karlberg, T.,Herzog, N.,Thorsell, A.G.,Gross, A.,Feijs, K.L.,Verheugd, P.,Kursula, P.,Nijmeijer, B.,Kremmer, E.,Kleine, H.,Ladurner, A.G.,Schuler, H.,Luscher, B.; Recognition of Mono-ADP-Ribosylated ARTD10 Substrates by ARTD8 Macrodomains.; Structure, 21:462-475, 2013; PubMed: 23473667; DOI: 10.1016/j.str.2012.12.019

実験手法

X-RAY DIFFRACTION (2.2 Å)