3UV1

Crystal structure a major allergen from dust mite

3UV1 の概要

• エントリーDOI: 10.2210/pdb3uv1/pdb
• 分子名称: Der f 7 allergen (2 entities in total)
• 機能のキーワード: super-roll, allergen
• 由来する生物種: Dermatophagoides farinae (American house dust mite)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 44394.74

構造登録者

Tan, K.W.,Kumar, T.,Chew, F.T.,Mok, Y.K. (登録日: 2011-11-29, 公開日: 2012-10-17, 最終更新日: 2024-10-30)

主引用文献

Tan, K.W.,Jobichen, C.,Ong, T.C.,Gao, Y.F.,Tiong, Y.S.,Wong, K.N.,Chew, F.T.,Sivaraman, J.,Mok, Y.K.
Crystal Structure of Der f 7, a Dust Mite Allergen from Dermatophagoides farinae.
Plos One, 7:e44850-e44850, 2012

PubMed Abstract: Der f 7 is the group 7 allergen from the dust mite Dermatophagoides farinae, homologous to the major allergen Der p 7 from D. pteronyssinus. Monoclonal antibody that bind to residues Leu48 and Phe50 was found to inhibit IgE binding to residue Asp159, which is important for the cross-reactivity between Der f 7 and Der p 7.

PubMed: 22970319
DOI: 10.1371/journal.pone.0044850

実験手法

X-RAY DIFFRACTION (2 Å)