3URF

Human RANKL/OPG complex

3URF の概要

• エントリーDOI: 10.2210/pdb3urf/pdb
• 分子名称: Tumor necrosis factor ligand superfamily member 11, soluble form, Tumor necrosis factor receptor superfamily member 11B, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
• 機能のキーワード: cystein-rich domain, beta-sandwich, cytokine
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Isoform 1: Cell membrane; Single-pass type II membrane protein. Isoform 3: Cell membrane; Single-pass type II membrane protein. Isoform 2: Cytoplasm (By similarity). Tumor necrosis factor ligand superfamily member 11, soluble form: Secreted (By similarity): O14788; Secreted: O00300
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 38383.07

構造登録者

Wang, X.Q.,Luan, X.D.,Lu, Q.Y. (登録日: 2011-11-22, 公開日: 2012-07-11, 最終更新日: 2020-07-29)

• 主引用文献: Luan, X.D.,Lu, Q.Y.,Jiang, Y.N.,Zhang, S.Y.,Wang, Q.,Yuan, H.H.,Zhao, W.M.,Wang, J.W.,Wang, X.Q.; Crystal Structure of Human RANKL Complexed with Its Decoy Receptor Osteoprotegerin; J.Immunol., 189:245-252, 2012; PubMed: 22664871; DOI: 10.4049/jimmunol.1103387

実験手法

X-RAY DIFFRACTION (2.701 Å)