3URB
Crystal Structure of PTE mutant H254G/H257W/L303T/M317L/I106C/F132I/L271I/K185R/I274N/A80V/R67H
Summary for 3URB
Entry DOI | 10.2210/pdb3urb/pdb |
Related | 3UPM 3UR2 3UR3 3URA 3URN 3URQ |
Descriptor | Parathion hydrolase, IMIDAZOLE, DIETHYL HYDROGEN PHOSPHATE, ... (5 entities in total) |
Functional Keywords | metalloenzyme, tim barrel, nerve agents, phosphotriesterase, hydrolase |
Biological source | Brevundimonas diminuta |
Cellular location | Cell membrane; Peripheral membrane protein: P0A434 |
Total number of polymer chains | 2 |
Total formula weight | 71537.53 |
Authors | Tsai, P.,Fox, N.G.,Li, Y.,Barondeau, D.P.,Raushel, F.M. (deposition date: 2011-11-21, release date: 2012-08-01, Last modification date: 2023-12-06) |
Primary citation | Tsai, P.C.,Fox, N.,Bigley, A.N.,Harvey, S.P.,Barondeau, D.P.,Raushel, F.M. Enzymes for the homeland defense: optimizing phosphotriesterase for the hydrolysis of organophosphate nerve agents. Biochemistry, 51:6463-6475, 2012 Cited by PubMed: 22809162DOI: 10.1021/bi300811t PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.77 Å) |
Structure validation
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