3UQ2
Crystal structure of the post-catalytic product complex of polymerase lambda with an rCMP inserted opposite a templating G and dAMP inserted opposite a templating T at the primer terminus.
Summary for 3UQ2
Entry DOI | 10.2210/pdb3uq2/pdb |
Related | 3MGH 3MGI 3UPQ 3UQ0 3UQ1 |
Descriptor | DNA polymerase lambda, 5'-D(*CP*GP*GP*CP*TP*GP*TP*AP*CP*TP*G)-3', 5'-D(*CP*AP*GP*TP*AP)-R(P*CP*A)-3', ... (8 entities in total) |
Functional Keywords | dna polymerase lambda, ribonucleotide incorporation, protein conformation, transferase, lyase-dna complex, lyase/dna |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus: Q9UGP5 |
Total number of polymer chains | 4 |
Total formula weight | 43608.69 |
Authors | Gosavi, R.A.,Moon, A.F.,Kunkel, T.A.,Pedersen, L.C.,Bebenek, K. (deposition date: 2011-11-18, release date: 2012-05-23, Last modification date: 2023-09-13) |
Primary citation | Gosavi, R.A.,Moon, A.F.,Kunkel, T.A.,Pedersen, L.C.,Bebenek, K. The catalytic cycle for ribonucleotide incorporation by human DNA Pol lambda Nucleic Acids Res., 40:7518-7527, 2012 Cited by PubMed: 22584622DOI: 10.1093/nar/gks413 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.25 Å) |
Structure validation
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