3UPA
A general strategy for the generation of human antibody variable domains with increased aggregation resistance
Summary for 3UPA
| Entry DOI | 10.2210/pdb3upa/pdb |
| Related | 3UPC |
| Descriptor | kappa light chain variable domain (2 entities in total) |
| Functional Keywords | immunoglobulin fold, immune system |
| Biological source | Homo sapiens (human) |
| Total number of polymer chains | 2 |
| Total formula weight | 23281.53 |
| Authors | Dudgeon, K.,Rouet, R.,Kokmeijer, I.,Langley, D.B.,Christ, D. (deposition date: 2011-11-17, release date: 2012-06-20, Last modification date: 2023-11-01) |
| Primary citation | Dudgeon, K.,Rouet, R.,Kokmeijer, I.,Schofield, P.,Stolp, J.,Langley, D.,Stock, D.,Christ, D. General strategy for the generation of human antibody variable domains with increased aggregation resistance Proc.Natl.Acad.Sci.USA, 109:10879-10884, 2012 Cited by PubMed: 22745168DOI: 10.1073/pnas.1202866109 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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