3UON

Structure of the human M2 muscarinic acetylcholine receptor bound to an antagonist

3UON の概要

• エントリーDOI: 10.2210/pdb3uon/pdb
• 分子名称: Human M2 muscarinic acetylcholine, receptor T4 lysozyme fusion protein, (3R)-1-azabicyclo[2.2.2]oct-3-yl hydroxy(diphenyl)acetate, beta-D-glucopyranose, ... (5 entities in total)
• 機能のキーワード: g protein-coupled receptor, gpcr, acetylcholine receptor, signaling protein-antagonist complex, signaling protein/antagonist
• 由来する生物種: Homo sapiens; 詳細
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 53283.02

構造登録者

Haga, K.,Kruse, A.C.,Asada, H.,Yurugi-Kobayashi, T.,Shiroishi, M.,Zhang, C.,Weis, W.I.,Okada, T.,Kobilka, B.K.,Haga, T.,Kobayashi, T. (登録日: 2011-11-16, 公開日: 2012-02-01, 最終更新日: 2023-09-13)

• 主引用文献: Haga, K.,Kruse, A.C.,Asada, H.,Yurugi-Kobayashi, T.,Shiroishi, M.,Zhang, C.,Weis, W.I.,Okada, T.,Kobilka, B.K.,Haga, T.,Kobayashi, T.; Structure of the human M2 muscarinic acetylcholine receptor bound to an antagonist.; Nature, 482:547-551, 2012; PubMed: 22278061; DOI: 10.1038/nature10753

実験手法

X-RAY DIFFRACTION (3 Å)